Discover Anaveon®’s Publications

Anaveon has successfully taken ANV419 through preclinical trials, and the research and development so far has been documented and shared through publications.

You can read about the science behind the therapy, its validity and the results so far in these publications.

Selected Publications

Favorable pre-clinical safety profile of the novel not-alpha IL-2 agonist ANV419 supports first in human clinical development

SITC Annual Meeting. 2021 Nov 10-14

ANV419 is a novel CD122 selective IL 2/anti IL 2 antibody fusion protein with potent CD8+ T cell
and NK cell stimulatory function in vitro and in vivo

SITC Annual Meeting. 2020 Nov 9-14

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2

Sci Transl Med. 2016 Nov 30;8(367):367ra166.

Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms

Immunity. 2015 May 19;42(5):815-25

Improved IL-2 immunotherapy by selective stimulation of IL-2 receptors on lymphocytes and endothelial cells

Proc Natl Acad Sci U S A. 2010 Jun 29;107(26):11906-11

Selective stimulation of T cell subsets with antibody-cytokine immune complexes

Science. 2006 Mar 31;311(5769):1924-7